脉管病研究所

【概况】

上海市中西医结合脉管病研究所（简称脉研所），创建于1991年，是我国最早成立的中西医结合脉管病研究所。2019年经上海市中医药研究院组织专家评估正式确定该研究所成为上海中医药大学、上海市中医药研究院脉管病研究所。

脉研所依托上海市中西医结合医院，由全名著名中西医结合名老中医奚九一教授创建，是上海市少数几个市属研究所之一。经过30多年的发展，形成了“因虚感邪，因邪致瘀，分病辨邪，分期辨证，扶阳为本，祛邪为先”的奚氏脉管病学术思想。脉研所以奚九一学术思想、国家临床重点专科、国家中医药管理局全国脉管病医疗中心、国家中医药管理局糖尿病性足病协作组牵头单位、中国中西医结合周围血管壁创面及组织修复学组组长单位、中国创面联盟临床基地、长三角脉管病联盟理事长单位为支撑条件，目前围绕脉管病开展名中医学术思想研究、临床疗效评价、发病机制和中药作用机制研究、院内制剂开发等系列研究，聚焦“一创”（泛血管相关性创面）；“三病”（奚氏糖尿病足、肢体动脉硬化闭塞症、静脉性及炎症性血管病）；三方（三黄消炎方、软坚清脉方、清络通脉方）开展临床评价、基础研究、新药开发等工作，积极推进科研成果转化。

脉研所由名中医传承工作室、临床研究室、基础和新药研究室、中医外治室、测试中心和学术委员会组成。第一任所长奚九一教授，第二任所长曹烨民教授，第三人所长曹永兵教授。现有所长1人，副所长3人，专职人员12人；2人具有中医学博士学位，2人具有中西医结合博士学位，2人具有药理学博士学位，1人具有中药学博士学位，1人具有理学博士学位，3人具有中医学硕士学位，1人具有医学硕士学位，1人具有药学硕士学位，1人具有遗传学硕士学位。 高级职称5人，副高级职称2人，中级职称5人。 现有博士生导师2人，硕士生导师7人。为推进脉管病病理和新靶标发现、药理机制研究、创新中药研发提供了有力的团队支撑。

经过30年的发展，脉管病研究所逐步建立了基础和临床研究相结合的科研体系，先后荣获上海市科技进步二、三等奖，国家卫生部科技进步三等奖等多种奖项。自2019年至今研究所共承担包括国家自然基金、“重大新药创制”科技重大专项课题在内的各级课题60余项，共发表文章70余篇，其中SCI收入论文50余篇，申请发明专利8项，授权2项。

近年来，研究所通过组织架构的重组、人才梯队的优化、实验条件的完善、管理制度的规范，进一步推进研究所发展。目前已完成近1500平方米系统化多功能实验室的建设，初步搭建了重要的科研共享平台，包括分子生物学平台、细胞生物学平台、免疫学研究平台、蛋白质研究平台、微生物研究平台、光谱分析平台、组织病理平台、临床研究平台、中药开发平台、实验动物平台（大鼠、小鼠、斑马鱼、果蝇等）等功能性平台以及生物样本库。平台配备价值4000多万元的各类科研仪器设备200多台件，包含但不限于全光谱流式细胞仪、分选流式细胞仪、流式细胞仪、高内涵成像与分析系统、超高分辨激光共聚焦显微系统、激光共聚焦显微拉曼光谱仪、微量等温滴定量热仪、蛋白纯化系统、蛋白结晶筛选系统、Beckman超速离心机、BioTek多功能酶标仪、离题血管研究系统、动物生理信号采集系统等先进科研仪器，可用于系统的病理学、药理学和创新中药开发研究。

【联系方式】

地址：上海市虹口区保定路230号6号楼15楼脉管病研究所

电话：021- 65785707

E-mail: shpharmforum@163.com

Shanghai TCM-Integrated Institute of Vascular Disease

Our responsibilities

The Institute was founded in 1991. Our major responsibilities are as follows:

1. To study the academic thoughts of famous Traditional Chinese Medicine practitioners focusing on vascular diseases

2. To explore the new pathological and new target of vascular diseases

3. To create innovative drugs for the prevention and treatment of vascular diseases

…

Our achievements

By the end of 2024, we have undertaken 61 longitudinal projects (including 10 national projects and 22 provincial and ministerial projects) and the approved contract funds were more than 57 million RMB.

We’ve led and published 4 occupation and group standards on Vascular Diseases

and served as the chief editor or co-editor of 6 guidelines. In terms of science and technology awards, we have won the second prize of Shanghai Science and Technology Progress Award, second Prize of Science and Technology Award of China Association of Chinese Medicine, third Prize of the Science and Technology Award of the Chinese Society of Integrated Traditional Chinese and Western Medicine. The team has published more than 81 academic papers, edited more than 20 textbooks and monographs, and trained more than 43 masters and doctors.

Our ongoing activities

1. Deepen the theoretical research on Xi Jiuyi's academic thoughts

2. Application and basic research of TCM in the prevention and treatment of vascular diseases (Pan-vascular-related wounds, Arteriosclerosis obliterans, Venous and inflammatory vascular diseases.)

3. Conducting research projects on the anti-diabetic ulcer foot effect of San Huang Xiao Yan recipe and Chenlanhua Granules

4. The new drug development of the in-hospital preparation Ruanjian Qingmai Granules.

…

Our staff

The institute has 1 director, 3 vice-director and 12 full-time staff members, Regarding educational background, 2 has doctorate degree of Chinese medicine, 2 has doctorate degree of Integrated Traditional Chinese and Western Medicine, 2 has doctorate degree of Pharmacology, 1 has doctorate degree of Traditional Chinese Medicine, 1 has doctorate degree of Science , 3 have Master degree of Chinese medicine , 1 has Master degree of Medicine and 1 has Master degree of Pharmacy, 1 has Master degree of Genetics 5 of them has senior title, 2 has vice-senior title and 5 have middle titles.

Contact Us

Telephone: 021-65785707

Fax: 021-65785707

E-mail: shpharmforum@163.com

Address: Shanghai TCM-Integrated Institute of Vascular Disease, 15th Floor, Building 6, Shanghai Hospital of Integrated Traditional Chinese and Western Medicine, No. 230, Baoding Road, Shanghai